| Scofield Homes Inc | B | 1982 | Active |
| Scorpion Renovation & Development Inc | B | 2012 | Active |
| SD Cabinet Design Inc | B | 2024 | Active |
| SD Concrete Solutions LLC | A, B | 2024 | Active |
| SD Evse | B | 2023 | Active |
| SD Remodel Experts | B + C33 | 2019 | Active |
| SD Strong Construction | B | 2021 | Active |
| SD Wood Cabinet Construction | B | 2019 | Active |
| Sdair | B + C20, C38 | 2010 | Active |
| SDFS Construction & Restoration | B + C27, C33, D06 | 2000 | Active |
| Sdstature | B + C51 | 2014 | Active |
| SDVS Construction | B | 2026 | Active |
| Seabury Construction Inc | B | 2007 | Active |
| Seal Design & Build Inc | B | 2026 | Active |
| Seaside Construction Group | B | 2026 | Active |
| Send It Construction LLC | B | 2025 | Active |
| Sendolla Construction | B | 2026 | Active |
| Senko Prefab Install | B + D34 | 2024 | Active |
| Sentinel Built Inc | B | 2022 | Active |
| Sentinel Secure Build | B | 2026 | Active |
| Servi-Tek Engineering & Facility Solutions LLC | B | 2026 | Active |
| Service Solutions Corporation | B | 2015 | Active |
| Servpro | B + ASB | 2009 | Active |
| Servpro Of Centre City / Uptown | B + ASB, C21, C36 +2 | 2018 | Active |
| Servpro Of Point Loma | B | 2019 | Active |
| Servpro Of San Diego East | B + D64 | 2020 | Renew by Dec 31, 2026 |
| Settimio Porco & Sons Contractor Incorporated | B + C29 | 1977 | Active |
| Seven Home Improvement Inc | B | 2021 | Active |
| Seventy 1 Environmental Inc | A | 2012 | Active |
| Seville Property MGMT Design & Remodel | B + C33 | 2018 | Renew by Dec 31, 2026 |
| Sextant Designs | B | 2022 | Active |
| SG Creative Construction Corp | B | 2025 | Active |
| Shark Remodeling Corp | B2 | 2025 | Active |
| She Manages Properties Inc | B | 2002 | Active |
| Shear Force Construction Services Inc | B | 2014 | Active |
| Shermans Builders | B | 2017 | Active |
| Shermans Builders Inc | B | 2025 | Active |
| Sherwood Mechanical Inc | A + C36 | 2003 | Active |
| Shirari Design Build | B | 2021 | Active |
| Shiro Builders Group Inc | B + C27 | 2026 | Active |
| Shugarman's Bath | B + C36 | 2019 | Active |
| Silva Custom Builders | B | 2007 | Active |
| Silver Sparrow Homes | B | 2003 | Active |
| Silver Strand Construction Inc | B | 2021 | Active |
| Silverline Construction | B | 1999 | Active |
| Silverstrand Construction | A, B + D34 | 2009 | Active |
| Simax Group Inc | B | 2021 | Active |
| Simpson Bobby & Sons Enterprises Inc | A, B | 2016 | Renew by Dec 31, 2026 |
| Simpson General Contractors Inc | B + C6 | 2005 | Active |
| Sitepro General Contracting Services LLC | B | 2025 | Active |
| Sky Construction & Painting Inc | B + C33 | 2023 | Active |
| Sky Remodeling Design And Build Inc | B | 2024 | Active |
| Skys And Son's Enterprises Inc | B | 2010 | Active |
| Smart Dry Restoration | B + C36 | 2020 | Active |
| Smart Roofing And Restoration | B + C2, C39 | 2024 | Active |
| Snapadu LLC | B | 2021 | Active |
| Snguyen002 Services LLC | B | 2026 | Active |
| Snyder Geologic Inc | A | 2014 | Renew by Dec 31, 2026 |
| Socal Building Group | A, B | 2022 | Active |
| Socal Maintenance Inc | B | 2017 | Active |
| Socal Tile And Stone Inc | B + C39, C54 | 2015 | Active |
| Sol Design Build Inc | B | 2026 | Active |
| Sol Home Improvements Inc | B2 | 2025 | Active |
| Solar Turbines Incorporated | A | 1984 | Active |
| Solid Construction & Remodeling Inc | B | 2025 | Active |
| Solid Green Limited Liability Co | B + C39 | 2021 | Active |
| Solid Line Builders | B | 2026 | Active |
| Solid Property Services Inc | B | 2010 | Active |
| Solid Rock Custom Builders Inc | B | 2008 | Active |
| Solidworx Inc | B | 2021 | Active |
| Solion Construction | B + C10 | 2021 | Active |
| Soltek Pacific Construction Company | A, B | 2006 | Active |
| Solv Energy LLC | A, B + C10, C46 | 2021 | Active |
| Son Light Technology Corporation | B | 1984 | Active |
| Sonshine Painting | B + C27, C33 | 2021 | Active |
| Sopac Builders Inc | B | 2026 | Active |
| Soto Construction General Contractor | B | 2021 | Active |
| Soundproof San Diego Inc | B + C2 | 2017 | Active |
| South Coast Builders - Design And Build | B | 2026 | Active |
| South Coast Flooring & Installations | B + C15, C54, D52 | 1995 | Active |
| South Coast Specialty Systems Inc | B + C33, C39 | 2005 | Active |
| Southern California Income Property Services Inc | B + C33 | 2023 | Active |
| Southland Electric Inc | B + C10 | 1978 | Active |
| Southland Technology Inc | B + C7, C10 | 2005 | Active |
| Southwest Erosion Control & Grading Inc | A | 2025 | Active |
| Southwest Millworks Inc | B + C6 | 2001 | Active |
| Souza And Souza Construction Inc | B | 2005 | Active |
| SPC Plumbing | B + C36 | 2021 | Active |
| Specialty Solutions Inc | B + D34 | 2013 | Active |
| Spectrum Renovations | B | 1994 | Active |
| Speedway Constructors Inc | A, B | 2005 | Active |
| Speedy Renovate Contractor | B | 2024 | Active |
| Spring Hill Services LLC | B + C7 | 2026 | Active |
| Spyglass Construction | B | 2016 | Active |
| SQP Construction Inc | B + C8 | 2013 | Active |
| Square Contracting | B | 2020 | Renew by Dec 31, 2026 |
| Squared Away Builders Inc | B | 2023 | Active |
| SS Building LLC | B + C35 | 2019 | Active |
| Stafford David Construction Inc | B | 2009 | Active |
| Stallion Homes Remodeling | B, B2 | 2023 | Active |